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The comparison of blood levels of oestradiol, testosterone, prolactin, and sex-hormone binding globulin (SHBG) was made of 3250 rural Chinese and 300 British women, aged 35 to 64. To reduce the number of assays performed the blood samples were combined so as to form 390 and 30 pools, respectively. The Chinese had significantly less oestradiol and testosterone. Prolactin levels were similar in both races. SHBG was significantly lower in postmenopausal British women. In the Chinese women, testosterone was positively and prolactin negatively correlated with breast cancer mortality.

Original publication




Journal article


Breast Cancer Res Treat

Publication Date



18 Suppl 1


S41 - S45


Adult, Age Factors, China, Estradiol, Female, Humans, Menarche, Menopause, Middle Aged, Prolactin, Rural Population, Sex Hormone-Binding Globulin, Testosterone, United Kingdom