Professor Sasha Shepperd

Contact information

Email
sasha.shepperd@ndph.ox.ac.uk

Research groups

Ethnicity and Breast Cancer

Websites

Ethnicity and breast cancer
Funded by the Prevention and Population Research Committee at Cancer Research UK (CI Toral Gathani)
Old Age Neuroscience and the ORCHARD portfolio
Nuffield Department of Clinical Neurosciences

Sasha Shepperd

BA, MSc, DPhil

Professor of Health Services Research & Interim Director of HERC

Co-lead of the Applied Health Research Unit
Oxford Population Health lead for equality, diversity and inclusion

Sasha’s research uses epidemiological methods, randomised trials and evidence synthesis to answer pressing health service/systems questions, with a focus on population ageing. Sasha was the chief investigator of a NIHR funded multi-site randomised trial of Hospital at Home vs hospital admission that was awarded the BGS Dhole-Eddlestone Memorial prize in 2023 and contributed to the evidence supporting NHS England’s virtual ward programme. Currently her research includes understanding the impact of inequalities that drive the need for social care by an older population, she is a co-investigator on CRUK funded research (led by Toral Gathani) on barriers and facilitators to the early diagnosis of breast cancer in ethnic minority women and a co-lead for the Cochrane Thematic Group: People, Health Systems and Public Health.

After an undergraduate degree in psychology from the University of Vermont, Sasha completed a master's at the Harvard School of Public Health and a DPhil at the University of Oxford.

Key publications

Vegetarian diets and cancer risk: pooled analysis of 1.8 million women and men in nine prospective studies on three continents.

Dunneram Y. et al, (2026), Br J Cancer

Kidney function and mortality in Mexico: prospective study of 130 000 adults

Aguilar Ramirez D. et al, (2026), Kidney Medicine

encoders reveal polyunsaturated fatty acids (PUFA)-Related metabolic signature linked to cancer risk.

Breeur M. et al, (2026), EBioMedicine, 124

Diet-wide association study of foods and nutrients with hip fracture risk: a prospective cohort study of 27,318 incident cases among 541,887 postmenopausal women

Tao Y. et al, (2026)

Breast Events After Treatment of Ductal Carcinoma In Situ in Women: A Population-Based Study.

Chen Q. et al, (2026), Cancer Med, 15

The circulating proteome and cancer risk: a systematic literature review and meta-analysis of 26 prospective studies with genetic validation.

Dillman A. et al, (2026), EBioMedicine, 124

Changing patterns in tongue, oral cavity, laryngeal and hypopharyngeal squamous cell carcinomas in New Zealand: Incidence, trends and survival from 2006 to 2022.

Win Myint TT. et al, (2026), Cancer Epidemiol, 101

Gender reporting across regions and time in psychological studies: a scoping review of studies in psychological Science between 2019 and 2024.

Chen T., (2026), Res Integr Peer Rev, 11

Reducing locoregional treatments in low risk early invasive breast cancer.

Potter S. et al, (2026), Eur J Surg Oncol, 52

ntibody Responses to 11 Fusobacterium Proteins and Colorectal Cancer-Specific and Overall Survival in the EPIC Cohort.

Michaud DS. et al, (2026), Cancer Epidemiol Biomarkers Prev, 35, 88 - 94

Genetically determined body mass index is associated with diffuse large B-cell lymphoma in polygenic and Mendelian randomization analyses.

Moore A. et al, (2026), Int J Cancer, 158, 45 - 59

Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition.

Manfredi L. et al, (2025), J Epidemiol Community Health, 80, 3 - 9

The gut microbiome mediates the association between a flavonoid-rich diet and MASLD in a population-level analysis.

Bell W. et al, (2025), Eur J Nutr, 65

Prevalence of cognitive morbidity including delirium in 51,202 emergency hospital admissions across 29 medical and surgical specialties in ORCHARD-EPR: a cross-sectional study.

Boucher EL. et al, (2025), EClinicalMedicine, 90

Trends and disparities in locoregional treatment of programme-detected ductal carcinoma in situ in New Zealand women, 1999-2022.

Chen Q. et al, (2025), Cancer Epidemiol, 99

Prospective associations of diabetes with 15 cancers in 2.2 million UK and Chinese adults.

Liu B. et al, (2025), J Natl Cancer Inst, 117, 2477 - 2487

Proactive Integrated Consultation-Liaison Psychiatry for older medical inpatients: The HOME Study RCT of its effectiveness and cost-effectiveness.

Sharpe M. et al, (2025), Health Soc Care Deliv Res, 13, 1 - 85

Public Health.

Maccora J. et al, (2025), Alzheimers Dement, 21 Suppl 6

Evaluation of the 4Kscore Test in Relation to Subsequent Risk of Aggressive Prostate Cancer in the European Prospective Investigation into Cancer and Nutrition.

Smith-Byrne K. et al, (2025), Cancer Epidemiol Biomarkers Prev, 34, 2058 - 2067

Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study.

Majidi A. et al, (2025), J Natl Cancer Inst, 117, 2343 - 2351

Disparities in time to breast cancer surgery in New Zealand by level of neighbourhood deprivation: a population-based study.

Boyle L. et al, (2025), Cancer Causes Control, 36, 1499 - 1510

Prospective evaluation of circulating plasma thyroid hormones concentrations and breast cancer risk in the EPIC cohort.

His M. et al, (2025), EBioMedicine, 121

Temporal trends in hospital-recorded pulmonary embolism in England before, during and after the COVID-19 pandemic (2008-2024): a population-based observational study.

Zhong X. et al, (2025), Lancet Reg Health Eur, 58

Blood Pressure and Mortality in Mexico City: A Mendelian Randomization Study.

Turner M. et al, (2025), Hypertension, 82, 1896 - 1905

Lifestyle changes and postmenopausal breast cancer risk in women from the European Prospective Investigation into Cancer and Nutrition.

Vasson F. et al, (2025), Breast Cancer Res, 27

Multi-cohort high-dimensional proteomics reveals early risk markers for lymphoid cancer subtypes.

Kolijn PM. et al, (2025), Nat Commun, 16

Social inequalities in the use of formal and informal home care in older women: evidence from a large UK cohort study.

Quinn M. et al, (2025), Age Ageing, 54

Trends and variation in the incidence of hip fracture in England before, during, and after the COVID-19 pandemic (2014-2024): a population-based observational study.

Webster J. et al, (2025), Lancet Reg Health Eur, 57

dvanced epithelial ovarian cancer in older patients.

Cullimore V. et al, (2025), Int J Gynecol Cancer, 35

The plasma proteome of plant-based diets: Analyses of 2920 proteins in 49,615 people.

Tong TYN. et al, (2025), Clin Nutr, 53, 144 - 154

Clinicopathological Characteristics and Oncologic Outcomes of Endometrioid Ovarian Carcinoma: A Retrospective Study from a Tertiary Cancer Centre.

Pappa C. et al, (2025), Biomedicines, 13

Proteogenomic and observational evidence implicate ANGPTL4 as a potential therapeutic target for colorectal cancer prevention.

Yarmolinsky J. et al, (2025), J Natl Cancer Inst, 117, 1836 - 1847

Statin use and breast cancer-specific mortality and recurrence: a systematic review and meta-analysis including the role of immortal time bias and tumour characteristics.

Scott OW. et al, (2025), Br J Cancer, 133, 539 - 554

Histological types of invasive breast cancer in 830,000 women diagnosed in England during 1988–2016

Probert J. et al, (2025), Journal of Pathology Clinical Research, 11

Delirium prevalence, diagnostic uncertainty and outcomes in ORCHARD-EPR: validation against prospective reference cohorts.

Boucher EL. et al, (2025), Age Ageing, 54

Metabolic syndrome and risk of incident all-cause dementia, Alzheimer's disease and vascular dementia: a systematic review and meta-analysis of longitudinal studies.

Qureshi D. et al, (2025), Alzheimers Res Ther, 17

Alcohol and smoking habits in association with hepatocellular carcinoma risk.

Aglago EK. et al, (2025), Int J Cancer, 157, 644 - 657

Reassessing the association between age at menarche and cardiovascular disease: observational and Mendelian randomization analyses.

Tschiderer L. et al, (2025), Eur J Prev Cardiol, 32, 857 - 866

The effects of adjuvant endocrine therapy on long-term outcomes from ductal carcinoma in situ: a systematic review and meta-analysis.

Chen Q. et al, (2025), Breast, 82

Blood Pressure Lowering and Risk of Cancer: Individual Participant-Level Data Meta-Analysis and Mendelian Randomization Studies.

Nazarzadeh M. et al, (2025), JACC CardioOncol, 7, 609 - 623

Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis.

Córdova R. et al, (2025), Lancet Healthy Longev, 6

Sex differences in cancer incidence: prospective analyses in the UK Biobank.

Khan M. et al, (2025), Br J Cancer, 133, 216 - 226

Factors associated with health-related quality of life and financial toxicity among gynecological cancer patients in Southern Nigeria.

Ogamba CF. et al, (2025), Sci Rep, 15

Recent publications