History of AgeX

2007

The Prime Minister announces plans for eventual extension of the age range for routine breast screening offered by the NHS from 50-70 to 47-73 years. It is unclear when this would begin, providing an opportunity to obtain reliable evidence about the effects of extending the age range for screening.

2009

AgeX begins with a pilot study of the acceptability of randomisation of additional screening at 47-49 and 71-73 in seven breast screening centres in England.

2010

Randomisation into AgeX is extended to about five-sixths of the breast screening centres in England.

2012

The Independent UK Panel on Breast Screening concludes that, while breast screening at ages 50-70 confers significant benefit to women, the effects of breast screening at younger or older ages are uncertain.

2018

The Government’s Independent Breast Screening Review recommends that AgeX should continue until its planned end date, 2026. The Health Minister’s Parliamentary Statement also recommends continuation of AgeX as planned.

2020

Entry into AgeX closes with over four million women randomised.

2021 - 2031

Follow-up to December 2031 by electronic linkage to routinely collected medical records. There will be two reports  on breast cancer mortality. The first report will be on follow-up to December 2026 and the final report will be on follow-up to the end of December 2031.