Epidemiological Studies of Endometrial Cancer
Established in 2005
Data from 27,000 women
The Collaborative Group on Epidemiological Studies of Endometrial Cancer conducts pooled analyses of international data on endometrial cancer. Set up in 2005, the collaboration currently includes data on over 27,000 women with endometrial cancer from 36 studies worldwide.
The first meeting of the Collaboration was held in Oxford in 2007. The first paper from the collaboration, on the risk associated with oral contraceptives, was published in 2015 (Lancet Oncology), and showed that use of oral contraceptives confers long-term protection against endometrial cancer. Other current and planned work includes detailed analyses of the use of hormonal replacement therapy on the risk of endometrial cancer, as well as investigations into the role of reproductive and other factors on the risk of the disease.