A case-control study from Uganda found that the risk of Kaposi's sarcoma increased with increasing titre of antibodies against Kaposi's sarcoma-associated herpesvirus (KSHV) latent nuclear antigens, independently of HIV infection. Clinically, widespread Kaposi's sarcoma was more frequent among patients with HIV infection than in those without, but was not related to anti-KSHV antibody titres.

Original publication

DOI

10.1038/sj.bjc.6601113

Type

Journal article

Journal

Br J Cancer

Publication Date

04/08/2003

Volume

89

Pages

502 - 504

Keywords

Adolescent, Adult, Antibodies, Viral, Case-Control Studies, Female, HIV Infections, Herpesvirus 8, Human, Humans, Male, Risk Factors, Sarcoma, Kaposi, Seroepidemiologic Studies, Severity of Illness Index, Uganda